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Artificial Intelligence

Critical Components to the Safety of Antimethanogenic Feed Ingredients and Their Residues in Livestock-Derived Foods for Human Consumption

Environmental concerns regarding the agricultural sector encompass climate change issues and include methane emissions from ruminant livestock, including dairy and beef cattle, sheep and goats, which produce methane during ruminal digestive processes. Strategies to mitigate methanogenesis in ruminants include alternative electron sinks (e.g., nitrate), unique vegetable oils and oilseeds, plants’ secondary metabolites (e.g., tannins, saponins, flavonoids) and methanogen inhibitors. The methanogen inhibitors include the chemically synthesized 3-nitrooxypropanol (3-NOP) and bromoform, a halogenated methane analog and the major active ingredient for methanogenesis inhibition synthesized by the seaweed Asparagopsis. Antimethanogenic compounds, unique vegetable oils and plant-derived secondary metabolites are intended to be administered as feed additives and their residues, metabolites and other constituents may result in products destined for human food consumption (e.g., milk, meat). However, does intake of these constituents represent a concern for human food safety? This session will discuss the processes by which residues in livestock-derived foods for human consumption should be carefully evaluated and which studies are necessary to determine long-term impact on animal and human health and to conclude the safety of these feed materials. Further, the potential concerns associated with the use of antimethanogenic feed ingredients for ruminants, the challenges to determine safety margins for different species and product categories, and the current regulatory context will be highlighted. Speaker: M. Chiara Perego, PhD

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