What problem are you addressing? Ingested nutrients, nutraceuticals and functional foods transit through metabolic pathways influenced by genetics, epigenetics, the microbiome and environmental factors, contributing to heterogeneity in individual needs and responses. These factors also underlie differences in disease susceptibility and response to therapy. What are the most important points the viewers should know? The requirement for different segments of populations in precision health approaches. Precision health combined with spatially resolved data could help the target populations of interventions where resources are limited. Integration of big data related to genetic, epigenetic, microbiome, lifestyle and environmental factors is required to expand our understanding of the diversity of human metabolism in response to diet. What is the broader impact of this information? Based on the need of individuals, agriculture policy could focus on the required food production and reduce the food waste, and food industry could produce the necessary food and increase the use of the food residues. Nutraceuticals and functional foods could be based on need and play critical role for population. Speaker: Chin-Kung Wang, PhD